Attenuation of Acute Renal Injury After the Post-resuscitation Administration of Doxycycline in Surviving Newborn Piglets With Severe Hypoxia-Reoxygenation

Background: Asphyxiated neonates often have myocardial dysfunction and renal insufficiency. Previously we demonstrated that doxycycline improved cardio-renal function through matrix metalloproteinase (MMP)-2 inhibition in an acute swine model of neonatal hypoxia-reoxygenation. The prolonged cardio-r...

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Detalhes bibliográficos
Publicado no:Front Pediatr
Main Authors: Lee, Tze-Fun, Lu, Min, Pasquin, Matteo P., Schmölzer, Georg M., Cheung, Po-Yin
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Pediatrics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6439344/
https://ncbi.nlm.nih.gov/pubmed/30968002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fped.2019.00075
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