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Activation of Stat3 in Endothelial Cells Following Hypoxia-reoxygenation is Mediated by Rac1 and Protein Kinase C

Stat3 is an important transcription factor that regulates both proinflammatory and anti-apoptotic pathways in the heart. This study examined the mechanisms of activation of Stat3 in human endothelial cells following hypoxia/reoxygenation (H/R). By expression of constitutively active Rac1 mutant prot...

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Detalhes bibliográficos
Main Authors: Mattagajasingh, Subhendra N., Yang, Xiao Ping, Irani, Kaikobad, Mattagajasingh, Ilwola, Becker, Lewis C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3392026/
https://ncbi.nlm.nih.gov/pubmed/22791907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2012.02.008
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