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RNAi promotes heterochromatic silencing through replication-coupled release of RNA polII
Heterochromatin comprises tightly compacted repetitive regions of eukaryotic chromosomes. The inheritance of heterochromatin through mitosis requires RNA interference (RNAi), which guides histone modification (1) during the DNA replication phase of the cell cycle(2). Here, we show that the alternati...
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| Main Authors: | , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3391703/ https://ncbi.nlm.nih.gov/pubmed/22002604 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10501 |
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