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CENP-B preserves genome integrity at replication forks paused by Retrotransposon LTR

Centromere-binding protein B (CENP-B) is a widely conserved DNA binding factor associated with heterochromatin and centromeric satellite repeats1. In fission yeast, CENP-B homologs have been shown to silence Long Terminal Repeat (LTR) retrotransposons by recruiting histone deacetylases2. However, CE...

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Detalhes bibliográficos
Main Authors: Zaratiegui, Mikel, Vaughn, Matthew W., Irvine, Danielle V., Goto, Derek, Watt, Stephen, Bähler, Jürg, Arcangioli, Benoit, Martienssen, Robert A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3057531/
https://ncbi.nlm.nih.gov/pubmed/21151105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09608
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