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Structure of the Glycosyltransferase EryCIII in Complex with its Activating P450 Homologue EryCII
In the biosynthesis of the clinically important antibiotic erythromycin D, the glycosyltransferase (GT) EryCIII, in concert with its partner EryCII, attaches a nucleotide-activated sugar to the macrolide scaffold with high specificity. To understand the role of EryCII, we have determined the crystal...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Elsevier
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3391682/ https://ncbi.nlm.nih.gov/pubmed/22056329 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.10.036 |
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