Characteristic Features of Kynurenine Aminotransferase Allosterically Regulated by (Alpha)-Ketoglutarate in Cooperation with Kynurenine

Kynurenine aminotransferase from Pyrococcus horikoshii OT3 (PhKAT), which is a homodimeric protein, catalyzes the conversion of kynurenine (KYN) to kynurenic acid (KYNA). We analyzed the transaminase reaction mechanisms of this protein with pyridoxal-5′-phosphate (PLP), KYN and α-ketoglutaric acid (...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Okada, Ken, Angkawidjaja, Clement, Koga, Yuichi, Takano, Kazufumi, Kanaya, Shigenori
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2012
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3391261/
https://ncbi.nlm.nih.gov/pubmed/22792273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0040307
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk