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Molecular Determinants of Gem Protein Inhibition of P/Q-type Ca(2+) Channels
The RGK family of monomeric GTP-binding proteins potently inhibits high voltage-activated Ca(2+) channels. The molecular mechanisms of this inhibition are largely unclear. In Xenopus oocytes, Gem suppresses the activity of P/Q-type Ca(2+) channels on the plasma membrane. This is presumed to occur th...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3391154/ https://ncbi.nlm.nih.gov/pubmed/22589533 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.291872 |
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