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Direct inhibition of P/Q-type voltage-gated Ca(2+) channels by Gem does not require a direct Gem/Ca(v)β interaction

The Rem, Rem2, Rad, and Gem/Kir (RGK) family of small GTP-binding proteins potently inhibits high voltage-activated (HVA) Ca(2+) channels, providing a powerful means of modulating neural, endocrine, and muscle functions. The molecular mechanisms of this inhibition are controversial and remain largel...

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Sonraí Bibleagrafaíochta
Main Authors: Fan, Mingming, Buraei, Zafir, Luo, Huai-Rong, Levenson-Palmer, Rose, Yang, Jian
Formáid: Artigo
Teanga:Inglês
Foilsithe: National Academy of Sciences 2010
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2930421/
https://ncbi.nlm.nih.gov/pubmed/20679232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1007543107
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