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Direct inhibition of P/Q-type voltage-gated Ca(2+) channels by Gem does not require a direct Gem/Ca(v)β interaction
The Rem, Rem2, Rad, and Gem/Kir (RGK) family of small GTP-binding proteins potently inhibits high voltage-activated (HVA) Ca(2+) channels, providing a powerful means of modulating neural, endocrine, and muscle functions. The molecular mechanisms of this inhibition are controversial and remain largel...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2930421/ https://ncbi.nlm.nih.gov/pubmed/20679232 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1007543107 |
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