Calpain Induces N-terminal Truncation of β-Catenin in Normal Murine Liver Development: DIAGNOSTIC IMPLICATIONS IN HEPATOBLASTOMAS

Hepatic competence, specification, and liver bud expansion during development depend on precise temporal modulation of the Wnt/β-catenin signaling. Also, loss- and gain-of-function studies have revealed pleiotropic roles of β-catenin in proliferation and hepatocyte and biliary epithelial cell differ...

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Main Authors: Lade, Abigale, Ranganathan, Sarangarajan, Luo, Jianhua, Monga, Satdarshan P. S.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2012
Ábhair:
Developmental Biology
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3391133/
https://ncbi.nlm.nih.gov/pubmed/22613727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.378224
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