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Transforming Growth Factor β1 (TGF-β1) Suppresses Growth of B-cell Lymphoma Cells by p14(ARF)-dependent Regulation of Mutant p53

Previously we reported that TGF-β1-induced growth suppression was associated with a decrease in mutant p53 levels in B-cell lymphoma cells. The goal of the present study was to understand the mechanism involved in TGF-β1-mediated down-regulation of mutant p53. In RL and CA46, two B-cell lymphoma cel...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Chen, Gang, Ghosh, Paritosh, O'Farrell, Thomas, Munk, Rachel, Rezanka, Louis J., Sasaki, Carl Y., Longo, Dan L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3391099/
https://ncbi.nlm.nih.gov/pubmed/22621932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.351411
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