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The role of LRRK2 in inflammatory bowel disease
LRRK2 was recently identified as a major susceptibility gene for Crohn's disease (CD) by genome-wide association studies (GWAS). LRRK2 deficiency in mice confers enhanced susceptibility to experimental colitis. In this research highlight, we discuss the current understanding of LRRK2 in the con...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3391018/ https://ncbi.nlm.nih.gov/pubmed/22430149 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2012.42 |
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