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Critical role of P1-Runx1 in mouse basophil development

Runx1(P1N/P1N) mice are deficient in the transcription factor distal promoter-derived Runt-related transcription factor 1 (P1-Runx1) and have a > 90% reduction in the numbers of basophils in the BM, spleen, and blood. In contrast, Runx1(P1N/P1N) mice have normal numbers of the other granulocytes...

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Hlavní autoři: Mukai, Kaori, BenBarak, Maya J., Tachibana, Masashi, Nishida, Keigo, Karasuyama, Hajime, Taniuchi, Ichiro, Galli, Stephen J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3390962/
https://ncbi.nlm.nih.gov/pubmed/22611151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-12-399113
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