1α,25-Dihydroxyvitamin D(3) and its analog, 2-methylene-19-nor-(20S)-1α,25-dihydroxyvitamin D(3) (2MD), suppress intraocular pressure in non-human primates

Ocular hypertension is the greatest known risk factor for glaucoma that affects an estimated 70 million people worldwide. Lowering intraocular pressure (IOP) remains the mainstay of therapy in the management of glaucoma. By means of microarray analysis, we have discovered that 1α,25-dihydroxyvitamin...

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Autores principales: Kutuzova, Galina D., Gabelt, B’Ann T., Kiland, Julie A., Hennes-Beann, Elizabeth A., Kaufman, Paul L., DeLuca, Hector F.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3390938/
https://ncbi.nlm.nih.gov/pubmed/22198282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2011.10.022
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