1α,25-Dihydroxyvitamin D(3) and its analog, 2-methylene-19-nor-(20S)-1α,25-dihydroxyvitamin D(3) (2MD), suppress intraocular pressure in non-human primates

Ocular hypertension is the greatest known risk factor for glaucoma that affects an estimated 70 million people worldwide. Lowering intraocular pressure (IOP) remains the mainstay of therapy in the management of glaucoma. By means of microarray analysis, we have discovered that 1α,25-dihydroxyvitamin...

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Hlavní autoři: Kutuzova, Galina D., Gabelt, B’Ann T., Kiland, Julie A., Hennes-Beann, Elizabeth A., Kaufman, Paul L., DeLuca, Hector F.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3390938/
https://ncbi.nlm.nih.gov/pubmed/22198282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2011.10.022
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