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Evidence of a progressive motor dysfunction in Mucopolysaccharidosis type I mice
Mucopolysaccharidosis (MPS) type I (Hurler syndrome) is a lysosomal storage disorder characterized by deficiency of alpha-L-iduronidase (IDUA), intracellular storage of glycosaminoglycans (GAGs) and progressive neurological pathology. The MPS I mouse model provides an opportunity to study the pathop...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3390919/ https://ncbi.nlm.nih.gov/pubmed/22580166 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbr.2012.04.051 |
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