Notch ligand Delta-like 4 blockade attenuates atherosclerosis and metabolic disorders

Atherosclerosis and insulin resistance are major components of the cardiometabolic syndrome, a global health threat associated with a systemic inflammatory state. Notch signaling regulates tissue development and participates in innate and adaptive immunity in adults. The role of Notch signaling in c...

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Autors principals: Fukuda, Daiju, Aikawa, Elena, Swirski, Filip K., Novobrantseva, Tatiana I., Kotelianski, Victor, Gorgun, Cem Z., Chudnovskiy, Aleksey, Yamazaki, Hiroyuki, Croce, Kevin, Weissleder, Ralph, Aster, Jon C., Hotamisligil, Gökhan S., Yagita, Hideo, Aikawa, Masanori
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2012
Matèries:
PNAS Plus
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3390871/
https://ncbi.nlm.nih.gov/pubmed/22699504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1116889109
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