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Non-invasive prenatal diagnosis by massively parallel sequencing of maternal plasma DNA

The presence of foetal DNA in the plasma of pregnant women has opened up new possibilities for non-invasive prenatal diagnosis. The use of circulating foetal DNA for the non-invasive prenatal detection of foetal chromosomal aneuploidies is challenging as foetal DNA represents a minor fraction of mat...

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Detalles Bibliográficos
Autor Principal: Lo, Yuk Ming Dennis
Formato: Artigo
Idioma:Inglês
Publicado: The Royal Society 2012
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3390796/
https://ncbi.nlm.nih.gov/pubmed/22773950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.120086
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