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Signaling Active CD95 Receptor Molecules Trigger Co-translocation of Inactive CD95 Molecules into Lipid Rafts

The capability of soluble CD95L trimers to trigger CD95-associated signaling pathways is drastically increased by oligomerization. The latter can be achieved, for example, by antibodies recognizing a N-terminal epitope tag in recombinant CD95L variants or by genetic engineering-enforced formation of...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lang, Isabell, Fick, Andrea, Schäfer, Viktoria, Giner, Tina, Siegmund, Daniela, Wajant, Harald
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3390677/
https://ncbi.nlm.nih.gov/pubmed/22645131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.328211
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