Ataxin-1 Poly(Q)-induced Proteotoxic Stress and Apoptosis Are Attenuated in Neural Cells by Docosahexaenoic Acid-derived Neuroprotectin D1

Neurodegenerative diseases share two common features: enhanced oxidative stress and cellular inability to scavenge structurally damaged abnormal proteins. Pathogenesis of polyglutamine (poly(Q)) diseases involves increased protein misfolding, along with ubiquitin and chaperon protein-containing nucl...

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Autori principali: Calandria, Jorgelina M., Mukherjee, Pranab K., de Rivero Vaccari, Juan Carlos, Zhu, Min, Petasis, Nicos A., Bazan, Nicolas G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2012
Soggetti:
Lipids
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3390647/
https://ncbi.nlm.nih.gov/pubmed/22511762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.287078
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