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Selective Survival Rescue in 15-Lipoxygenase-1-deficient Retinal Pigment Epithelial Cells by the Novel Docosahexaenoic Acid-derived Mediator, Neuroprotectin D1

The integrity of the retinal pigment epithelial (RPE) cell is essential for the survival of rod and cone photoreceptor cells. Several stressors, including reactive oxygen species, trigger apoptotic damage in RPE cells preceded by an anti-inflammatory, pro-survival response, the formation of neuropro...

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Bibliographische Detailangaben
Hauptverfasser: Calandria, Jorgelina M., Marcheselli, Victor L., Mukherjee, Pranab K., Uddin, Jasim, Winkler, Jeremy W., Petasis, Nicos A., Bazan, Nicolas G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2719426/
https://ncbi.nlm.nih.gov/pubmed/19403949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.003988
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