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Hemerythrin-like Domain within F-box and Leucine-rich Repeat Protein 5 (FBXL5) Communicates Cellular Iron and Oxygen Availability by Distinct Mechanisms
Iron regulatory proteins play a principal role in maintaining cellular iron homeostasis by post-transcriptionally regulating factors responsible for iron uptake, utilization, and storage. An E3 ubiquitin ligase complex containing FBXL5 targets IRP2 for proteasomal degradation under iron- and oxygen-...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3390645/ https://ncbi.nlm.nih.gov/pubmed/22648410 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.360404 |
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