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Overexpression of the Coq8 Kinase in Saccharomyces cerevisiae coq Null Mutants Allows for Accumulation of Diagnostic Intermediates of the Coenzyme Q(6) Biosynthetic Pathway

Most of the Coq proteins involved in coenzyme Q (ubiquinone or Q) biosynthesis are interdependent within a multiprotein complex in the yeast Saccharomyces cerevisiae. Lack of only one Coq polypeptide, as in Δcoq strains, results in the degradation of several Coq proteins. Consequently, Δcoq strains...

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Autors principals: Xie, Letian X., Ozeir, Mohammad, Tang, Jeniffer Y., Chen, Jia Y., Jaquinod, Sylvie-Kieffer, Fontecave, Marc, Clarke, Catherine F., Pierrel, Fabien
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3390632/
https://ncbi.nlm.nih.gov/pubmed/22593570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.360354
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