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Combination of nifedipine and subtherapeutic dose of cyclosporin additively suppresses mononuclear cells activation of patients with rheumatoid arthritis and normal individuals via Ca(2+)–calcineurin–nuclear factor of activated T cells pathway
Abnormal Ca(2+)-mediated signalling contributes to the pathogenesis of rheumatoid arthritis (RA). However, the potential implication of calcium channel blocker in RA remained unknown. We hypothesized that nifedipine, an L-type calcium channel blocker, combined with a calcineurin inhibitor, could sup...
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| Main Authors: | , , , , , , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
Blackwell Publishing Ltd
2012
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3390498/ https://ncbi.nlm.nih.gov/pubmed/22385242 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2012.04563.x |
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