Combination of nifedipine and subtherapeutic dose of cyclosporin additively suppresses mononuclear cells activation of patients with rheumatoid arthritis and normal individuals via Ca(2+)–calcineurin–nuclear factor of activated T cells pathway

Abnormal Ca(2+)-mediated signalling contributes to the pathogenesis of rheumatoid arthritis (RA). However, the potential implication of calcium channel blocker in RA remained unknown. We hypothesized that nifedipine, an L-type calcium channel blocker, combined with a calcineurin inhibitor, could sup...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Lai, N-S, Yu, C-L, Yin, W-Y, Yu, H-C, Huang, H-B, Tung, C-H, Lu, M-C
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2012
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3390498/
https://ncbi.nlm.nih.gov/pubmed/22385242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2012.04563.x
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados