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CD137 deficiency does not affect development of airway inflammation or respiratory tolerance induction in murine models
The co-stimulatory molecule CD137 (4-1BB) plays a crucial role in the development and persistence of asthma, characterized by eosinophilic airway inflammation, mucus hypersecretion, airway hyperreactivity, increased T helper type 2 (Th2) cytokine production and serum immunoglobulin (Ig)E levels. We...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Blackwell Publishing Ltd
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3390483/ https://ncbi.nlm.nih.gov/pubmed/22519594 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2012.04572.x |
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