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The Murine CD137/CD137 Ligand Signalosome: A Signal Platform Generating Signal Complexity

CD137, a member of the TNFR family, is a costimulatory receptor, and CD137L, a member of the TNF family, is its ligand. Studies using CD137- and CD137L-deficient mice and antibodies against CD137 and CD137L have revealed the diverse and paradoxical effects of these two proteins in various cancers, a...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Choi, Beom K., Lee, Hyeon-Woo
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7758191/
https://ncbi.nlm.nih.gov/pubmed/33362756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.553715
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