Mannan-binding lectin (MBL)-associated serine protease-1 (MASP-1), a serine protease associated with humoral pattern-recognition molecules: normal and acute-phase levels in serum and stoichiometry of lectin pathway components

The pattern-recognition molecules mannan-binding lectin (MBL) and the three ficolins circulate in blood in complexes with MBL-associated serine proteases (MASPs). When MBL or ficolin recognizes a microorganism, activation of the MASPs occurs leading to activation of the complement system, an importa...

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Detalhes bibliográficos
Main Authors: Thiel, S, Jensen, L, Degn, S E, Nielsen, H J, Gál, P, Dobó, J, Jensenius, J C
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2012
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3390472/
https://ncbi.nlm.nih.gov/pubmed/22670777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2012.04584.x
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