Binding of hnRNP H and U2AF65 to Respective G-codes and a Poly-Uridine Tract Collaborate in the N50-5'ss Selection of the REST N Exon in H69 Cells

The splicing of the N exon in the pre-mRNA coding for the RE1-silencing transcription factor (REST) results in a truncated protein that modifies the expression pattern of some of its target genes. A weak 3'ss, three alternative 5'ss (N4-, N50-, and N62-5'ss) and a variety of putative...

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Detalhes bibliográficos
Main Authors: Ortuño-Pineda, Carlos, Galindo-Rosales, José Manuel, Calderón-Salinas, José Victor, Villegas-Sepúlveda, Nicolás, Saucedo-Cárdenas, Odila, De Nova-Ocampo, Mónica, Valdés, Jesús
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3390395/
https://ncbi.nlm.nih.gov/pubmed/22792276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0040315
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