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Inhibition of p38 MAPK activity promotes ex vivo expansion of human cord blood hematopoietic stem cells
Ex vivo expansion of hematopoietic stem cells (HSCs) depends on HSC self-renewing proliferation and functional maintenance, which can be negatively affected by HSC differentiation, apoptosis, and senescence. Therefore, inhibition of HSC senescence may promote HSC expansion. To test this hypothesis,...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3390192/ https://ncbi.nlm.nih.gov/pubmed/22258328 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00277-011-1397-7 |
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