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Autophagy regulates ROS-induced cellular senescence via p21 in a p38 MAPKα dependent manner
Oxidative stress induces not only senescence but also autophagy in a variety of mammalian cells. However, the relationship between these two has not been well established and thus, was investigated in the present study using WI38 human diploid fibroblasts (WI38 cells) as a model system. Our results...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3390188/ https://ncbi.nlm.nih.gov/pubmed/21816217 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exger.2011.07.005 |
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