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Carcinine Has 4-Hydroxynonenal Scavenging Property and Neuroprotective Effect in Mouse Retina

PURPOSE. Oxidative stress induces retinal damage and contributes to vision loss in progressive retinopathies. Carcinine (β-alanyl-histamine) is a natural imidazole-containing peptide derivative with antioxidant activity. It is predicted to scavenge 4-hydroxynonenal (4-HNE), a toxic product of lipid...

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Detalhes bibliográficos
Main Authors: Marchette, Lea D., Wang, Huaiwen, Li, Feng, Babizhayev, Mark A., Kasus-Jacobi, Anne
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3390180/
https://ncbi.nlm.nih.gov/pubmed/22577078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.11-9042
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