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RETINOL DEHYDROGENASE 12 DETOXIFIES 4-HYDROXYNONENAL IN PHOTORECEPTOR CELLS
Mutations of the photoreceptor retinol dehydrogenase 12 (RDH12) gene cause the early-onset retinal dystrophy Leber congenital amaurosis (LCA) by mechanisms not completely resolved. Determining the physiological role of RDH12 in photoreceptors is the focus of this study. Previous studies showed that...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2874966/ https://ncbi.nlm.nih.gov/pubmed/19686838 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2009.08.005 |
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