Acetylcholine Receptor Gating in a Zebrafish Model for Slow-Channel Syndrome

Slow-channel syndrome (SCS) is an autosomal-dominant disease resulting from mutations in muscle acetylcholine (ACh) receptor subunits. The associated fatigue and muscle degeneration are proposed to result from prolonged synaptic responses that overload intracellular calcium. Single-channel studies o...

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Autores principales: Walogorsky, Michael, Mongeon, Rebecca, Wen, Hua, Mandel, Gail, Brehm, Paul
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 2012
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3390176/
https://ncbi.nlm.nih.gov/pubmed/22674269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0158-12.2012
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