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Dihydrothymidine and thymidine glycol triphosphates as substrates for DNA polymerases: differential recognition of thymine C5-C6 bond saturation and sequence specificity of incorporation.

The ability of dihydrothymidine (DHdTTP) and thymidine glycol (dTTP-GLY) 5'-triphosphates to serve as substrates for different DNA polymerases was investigated. DHdTTP but not dTTP-GLY was used as a substrate by E. coli DNA polymerase I (Pol I). Within the detection limit of the assay used, nei...

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Pubblicato in:Nucleic Acids Res
Autori principali: Ide, H, Wallace, S S
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 1988
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC339014/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3060857/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/16.23.11339
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