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PTX3 Controls Activation of Matrix Metalloproteinase 1 and Apoptosis in Conjunctivochalasis Fibroblasts

PURPOSE. Conjunctivochalasis (CCh) is an age-related inflammatory ocular surface disease manifesting redundant, loose conjunctiva folds. The pathogenic role of Pentraxin 3 (PTX3) in controlling upregulation of matrix metalloproteinase 1 (MMP-1) and MMP-3 in CCh remains undefined. METHODS. Cytolocati...

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Autors principals: Guo, Ping, Zhang, Su-Zhen, He, Hua, Zhu, Ying-Ting, Tseng, Scheffer C. G.
Format: Artigo
Idioma:Inglês
Publicat: The Association for Research in Vision and Ophthalmology 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3390005/
https://ncbi.nlm.nih.gov/pubmed/22511625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.11-9103
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