Genes down-regulated in spaceflight are involved in the control of longevity in Caenorhabditis elegans

How microgravitational space environments affect aging is not well understood. We observed that, in Caenorhabditis elegans, spaceflight suppressed the formation of transgenically expressed polyglutamine aggregates, which normally accumulate with increasing age. Moreover, the inactivation of each of...

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Main Authors: Honda, Yoko, Higashibata, Akira, Matsunaga, Yohei, Yonezawa, Yukiko, Kawano, Tsuyoshi, Higashitani, Atsushi, Kuriyama, Kana, Shimazu, Toru, Tanaka, Masashi, Szewczyk, Nathaniel J., Ishioka, Noriaki, Honda, Shuji
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2012
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3390002/
https://ncbi.nlm.nih.gov/pubmed/22768380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep00487
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