Genes down-regulated in spaceflight are involved in the control of longevity in Caenorhabditis elegans

How microgravitational space environments affect aging is not well understood. We observed that, in Caenorhabditis elegans, spaceflight suppressed the formation of transgenically expressed polyglutamine aggregates, which normally accumulate with increasing age. Moreover, the inactivation of each of...

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Bibliographic Details
Main Authors: Honda, Yoko, Higashibata, Akira, Matsunaga, Yohei, Yonezawa, Yukiko, Kawano, Tsuyoshi, Higashitani, Atsushi, Kuriyama, Kana, Shimazu, Toru, Tanaka, Masashi, Szewczyk, Nathaniel J., Ishioka, Noriaki, Honda, Shuji
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3390002/
https://ncbi.nlm.nih.gov/pubmed/22768380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep00487
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