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Genes down-regulated in spaceflight are involved in the control of longevity in Caenorhabditis elegans

How microgravitational space environments affect aging is not well understood. We observed that, in Caenorhabditis elegans, spaceflight suppressed the formation of transgenically expressed polyglutamine aggregates, which normally accumulate with increasing age. Moreover, the inactivation of each of...

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Detalhes bibliográficos
Main Authors: Honda, Yoko, Higashibata, Akira, Matsunaga, Yohei, Yonezawa, Yukiko, Kawano, Tsuyoshi, Higashitani, Atsushi, Kuriyama, Kana, Shimazu, Toru, Tanaka, Masashi, Szewczyk, Nathaniel J., Ishioka, Noriaki, Honda, Shuji
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3390002/
https://ncbi.nlm.nih.gov/pubmed/22768380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep00487
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