Can we predict the effects of NF-κB inhibition in sepsis? Studies with parthenolide and ethyl pyruvate

BACKGROUND: Based partially on encouraging findings from preclinical models, interest has grown in therapeutic inhibition of NF-κB to limit inflammatory injury during sepsis. However, NF-κB also regulates protective responses, and predicting the net survival effects of such inhibition may be difficu...

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Bibliographic Details
Main Authors: Li, Xuemei, Su, Junwu, Cui, Xizhong, Li, Yan, Barochia, Amisha, Eichacker, Peter Q
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3389994/
https://ncbi.nlm.nih.gov/pubmed/19555300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/13543780903018880
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