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The evolving experience with therapeutic TNF inhibition in sepsis: considering the potential influence of risk of death
INTRODUCTION: Septic shock is highly lethal and its incidence is increasing. Although TNF-α plays a key role in sepsis pathogenesis, past efforts to therapeutically inhibit it had limited success. However, there is continued interest in such therapies and there are now ongoing Phase II sepsis trials...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3523300/ https://ncbi.nlm.nih.gov/pubmed/21961576 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/13543784.2011.623125 |
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