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Increasing Association Mapping Power and Resolution in Mouse Genetic Studies Through the Use of Meta-Analysis for Structured Populations
Genetic studies in mouse models have played an integral role in the discovery of the mechanisms underlying many human diseases. The primary mode of discovery has been the application of linkage analysis to mouse crosses. This approach results in high power to identify regions that affect traits, but...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Genetics Society of America
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3389987/ https://ncbi.nlm.nih.gov/pubmed/22505625 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.112.140277 |
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