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Increasing Association Mapping Power and Resolution in Mouse Genetic Studies Through the Use of Meta-Analysis for Structured Populations

Genetic studies in mouse models have played an integral role in the discovery of the mechanisms underlying many human diseases. The primary mode of discovery has been the application of linkage analysis to mouse crosses. This approach results in high power to identify regions that affect traits, but...

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Detalhes bibliográficos
Main Authors: Furlotte, Nicholas A., Kang, Eun Yong, Van Nas, Atila, Farber, Charles R., Lusis, Aldons J., Eskin, Eleazar
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3389987/
https://ncbi.nlm.nih.gov/pubmed/22505625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.112.140277
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