High-Resolution Mapping of Gene Expression Using Association in an Outbred Mouse Stock

Quantitative trait locus (QTL) analysis is a powerful tool for mapping genes for complex traits in mice, but its utility is limited by poor resolution. A promising mapping approach is association analysis in outbred stocks or different inbred strains. As a proof of concept for the association approa...

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Detalhes bibliográficos
Main Authors: Ghazalpour, Anatole, Doss, Sudheer, Kang, Hyun, Farber, Charles, Wen, Ping-Zi, Brozell, Alec, Castellanos, Ruth, Eskin, Eleazar, Smith, Desmond J., Drake, Thomas A., Lusis, Aldons J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2483929/
https://ncbi.nlm.nih.gov/pubmed/18688273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000149
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