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Similar effects of adenovirus E1A and glucocorticoid hormones on the expression of the metalloprotease stromelysin.
The stromelysin (sml) gene encodes a secreted protease which degrades components of the extracellular matrix. Transformation of NRK49F cells by the E1A region of adenovirus (Ad) type 5 or 12 reduces sml RNA levels, whereas various growth factors or EJras-mediated transformation stimulate sml gene ex...
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| Main Authors: | , , , , |
|---|---|
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
1988
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| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC338991/ https://ncbi.nlm.nih.gov/pubmed/3205738 |
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