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Bromination at C-5 of Pyrimidine and C-8 of Purine Nucleosides with 1,3-Dibromo-5,5-dimethylhydantoin

Treatment of the protected and unprotected nucleosides with 1,3-dibromo-5,5- dimethylhydantoin in aprotic solvents such as CH(2)Cl(2), CH(3)CN, or DMF effected smooth bromination of uridine and cytidine derivatives at C-5 of pyrimidine rings as well as adenosine and guanosine derivatives at C-8 of p...

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Hlavní autoři: Rayala, Ramanjaneyulu, Wnuk, Stanislaw F.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3389796/
https://ncbi.nlm.nih.gov/pubmed/22773864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2012.04.081
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