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Toward an Integrative Computational Model of the Guinea Pig Cardiac Myocyte

The local control theory of excitation-contraction (EC) coupling asserts that regulation of calcium (Ca(2+)) release occurs at the nanodomain level, where openings of single L-type Ca(2+) channels (LCCs) trigger openings of small clusters of ryanodine receptors (RyRs) co-localized within the dyad. A...

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Main Authors: Gauthier, Laura Doyle, Greenstein, Joseph L., Winslow, Raimond L.
格式: Artigo
語言:Inglês
出版: Frontiers Research Foundation 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3389778/
https://ncbi.nlm.nih.gov/pubmed/22783206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2012.00244
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