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Modelling oncogenic Ras/Raf signalling in the mouse
The Ras/Raf/MEK/ERK (or MAPK) signalling pathway relays extracellular stimuli to the nucleus, thereby regulating diverse cellular responses such as proliferation, growth, differentiation and apoptosis. Perturbation of these processes by aberrant MAPK signalling often leads to malignant transformatio...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2009
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3389704/ https://ncbi.nlm.nih.gov/pubmed/19201597 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gde.2008.12.006 |
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