Protein Kinase C-θ (PKC-θ) in Natural Killer Cell Function and Anti-Tumor Immunity

The protein kinase C-θ (PKCθ), which is essential for T cell function and survival, is also required for efficient anti-tumor immune surveillance. Natural killer (NK) cells, which express PKCθ, play a prominent role in this process, mainly by elimination of tumor cells with reduced or absent major h...

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Main Authors: Anel, Alberto, Aguiló, Juan I., Catalán, Elena, Garaude, Johan, Rathore, Moeez G., Pardo, Julián, Villalba, Martín
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Research Foundation 2012
Teme:
Immunology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3389606/
https://ncbi.nlm.nih.gov/pubmed/22783260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2012.00187
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