EWS/FLI-responsive GGAA-microsatellites exhibit polymorphic differences between European and African populations

The genetics of Ewing sarcoma development remain obscure. The incidence of Ewing sarcoma is ten-fold less in Africans as compared to Europeans, irrespective of geographic location, suggesting population-specific genetic influences. Since GGAA-containing microsatellites within key target genes are ne...

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Main Authors: Beck, Robert, Monument, Michael J., Watkins, W. Scott, Smith, Richard, Boucher, Kenneth M., Schiffman, Joshua D., Jorde, Lynn B., Randall, R. Lor, Lessnick, Stephen L.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3389350/
https://ncbi.nlm.nih.gov/pubmed/22749036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cancergen.2012.04.004
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