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Transforming growth factor-beta2 utilizes the canonical Smad-signaling pathway to regulate tissue transglutaminase expression in human trabecular meshwork cells

Transforming growth factor beta 2 (TGF-β2) is elevated in the aqueous humor of patients with glaucoma. This growth factor is known to increase extracellular matrix (ECM) deposition in the trabecular meshwork (TM) as well as increase intraocular pressure (IOP) in perfused human cultured anterior eye...

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Hlavní autoři: Tovar-Vidales, Tara, Clark, Abbot F., Wordinger, Robert J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3389044/
https://ncbi.nlm.nih.gov/pubmed/21722634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2011.06.011
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