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Crystallization and preliminary X-ray diffraction analysis of the high molecular weight ketoacyl reductase FabG4 complexed with NADH

FabG4 from Mycobacterium tuberculosis belongs to the high molecular weight ketoacyl reductases (HMwFabGs). The enzyme requires NADH for β-ketoacyl reductase activity. The protein was overexpressed, purified to homogeneity and crystallized as a FabG4–NADH complex. A mountable FabG4:NADH complex cryst...

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Autori principali: Dutta, Debajyoti, Bhattacharyya, Sudipta, Das, Amit Kumar
Natura: Artigo
Lingua:Inglês
Pubblicazione: International Union of Crystallography 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3388922/
https://ncbi.nlm.nih.gov/pubmed/22750865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309112020301
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