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Unprecedented deoxygenation at C-7 of the ansamitocin core during mutasynthetic biotransformations

We describe the unprecedented formation of six ansamitocin derivatives that are deoxygenated at C-7 of the ansamitocin core, obtained during fermentation experiments by employing a variety of Actinosynnema pretiosum mutants and mutasynthetic approaches. We suggest that the formation of these derivat...

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Detalhes bibliográficos
Main Authors: Knobloch, Tobias, Dräger, Gerald, Collisi, Wera, Sasse, Florenz, Kirschning, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: Beilstein-Institut 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3388874/
https://ncbi.nlm.nih.gov/pubmed/23015834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.8.96
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