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Unprecedented deoxygenation at C-7 of the ansamitocin core during mutasynthetic biotransformations
We describe the unprecedented formation of six ansamitocin derivatives that are deoxygenated at C-7 of the ansamitocin core, obtained during fermentation experiments by employing a variety of Actinosynnema pretiosum mutants and mutasynthetic approaches. We suggest that the formation of these derivat...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Beilstein-Institut
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3388874/ https://ncbi.nlm.nih.gov/pubmed/23015834 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.8.96 |
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