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Synthesis and characterization of Sant-75 derivatives as Hedgehog-pathway inhibitors
Sant-75 is a newly identified potent inhibitor of the hedgehog pathway. We designed a diversity-oriented synthesis program, and synthesized a series of Sant-75 analogues, which lays the foundation for further investigation of the structure–activity relationship of this important class of hedgehog-pa...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Beilstein-Institut
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3388872/ https://ncbi.nlm.nih.gov/pubmed/23015832 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.8.94 |
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